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Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
Adjuvanted protein vaccines offer high efficacy, yet most potent adjuvants remain proprietary. Several adjuvant compounds are being developed by the Vaccine Formulation Institute in Switzerland for global open access clinical use. In the context of the R21 malaria vaccine, in a mouse challenge model...
Autores principales: | Reinke, Sören, Pantazi, Eirini, Chappell, Gabrielle R., Sanchez-Martinez, Alexandra, Guyon, Romain, Fergusson, Joannah R., Salman, Ahmed M., Aktar, Anjum, Mukhopadhyay, Ekta, Ventura, Roland A., Auderset, Floriane, Dubois, Patrice M., Collin, Nicolas, Hill, Adrian V.S., Bezbradica, Jelena S., Milicic, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694591/ https://www.ncbi.nlm.nih.gov/pubmed/37913775 http://dx.doi.org/10.1016/j.xcrm.2023.101245 |
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