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Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading cause of cancer-related death. Hallmarks include desmoplasia with variable extracellular matrix (ECM) architecture and a complex microenvironment with spatially defined tumor, stromal, and immune populations. Neverthel...

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Detalles Bibliográficos
Autores principales: Mascharak, Shamik, Guo, Jason L., Foster, Deshka S., Khan, Anum, Davitt, Michael F., Nguyen, Alan T., Burcham, Austin R., Chinta, Malini S., Guardino, Nicholas J., Griffin, Michelle, Lopez, David M., Miller, Elisabeth, Januszyk, Michael, Raghavan, Shyam S., Longacre, Teri A., Delitto, Daniel J., Norton, Jeffrey A., Longaker, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694604/
https://www.ncbi.nlm.nih.gov/pubmed/37865092
http://dx.doi.org/10.1016/j.xcrm.2023.101248