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Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading cause of cancer-related death. Hallmarks include desmoplasia with variable extracellular matrix (ECM) architecture and a complex microenvironment with spatially defined tumor, stromal, and immune populations. Neverthel...
Autores principales: | Mascharak, Shamik, Guo, Jason L., Foster, Deshka S., Khan, Anum, Davitt, Michael F., Nguyen, Alan T., Burcham, Austin R., Chinta, Malini S., Guardino, Nicholas J., Griffin, Michelle, Lopez, David M., Miller, Elisabeth, Januszyk, Michael, Raghavan, Shyam S., Longacre, Teri A., Delitto, Daniel J., Norton, Jeffrey A., Longaker, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694604/ https://www.ncbi.nlm.nih.gov/pubmed/37865092 http://dx.doi.org/10.1016/j.xcrm.2023.101248 |
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