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Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma

Glioblastoma (GBM) is a hypoxic and “immune-cold” tumor containing rich stromal signaling molecules and cell populations, such as proteases and immunosuppressive tumor-associated macrophages (TAMs). Here, we seek to profile and characterize the potential proteases that may contribute to GBM immunosu...

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Detalles Bibliográficos
Autores principales: Pang, Lizhi, Guo, Songlin, Khan, Fatima, Dunterman, Madeline, Ali, Heba, Liu, Yang, Huang, Yuyun, Chen, Peiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694605/
https://www.ncbi.nlm.nih.gov/pubmed/37858339
http://dx.doi.org/10.1016/j.xcrm.2023.101238