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Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
Glioblastoma (GBM) is a hypoxic and “immune-cold” tumor containing rich stromal signaling molecules and cell populations, such as proteases and immunosuppressive tumor-associated macrophages (TAMs). Here, we seek to profile and characterize the potential proteases that may contribute to GBM immunosu...
Autores principales: | Pang, Lizhi, Guo, Songlin, Khan, Fatima, Dunterman, Madeline, Ali, Heba, Liu, Yang, Huang, Yuyun, Chen, Peiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694605/ https://www.ncbi.nlm.nih.gov/pubmed/37858339 http://dx.doi.org/10.1016/j.xcrm.2023.101238 |
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