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Identification and multicentric validation of soluble CDCP1 as a robust serological biomarker for risk stratification of NASH in obese Chinese

The definitive diagnosis of non-alcoholic steatohepatitis (NASH) currently relies on invasive and labor-intensive liver biopsy. Here, we identified soluble CUB domain-containing protein 1 (sCDCP1) as a top-ranked non-invasive biomarker for NASH using Olink-based proteomics in 238 obese individuals w...

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Detalles Bibliográficos
Autores principales: Jia, Xi, Song, Erfei, Liu, Yan, Chen, Jiarui, Wan, Pei, Hu, Yue, Ye, Dewei, Chakrabarti, Subrata, Mahajan, Hema, George, Jacob, Yan, Sen, Yu, Yongtao, Zhang, Guanghui, Wang, Yong, Yang, Wah, Wu, Lihong, Hua, Shuang, Lee, Chi Ho, Li, Huixin, Jiang, Xue, Lam, Karen S.L., Wang, Cunchuan, Xu, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694619/
https://www.ncbi.nlm.nih.gov/pubmed/37918406
http://dx.doi.org/10.1016/j.xcrm.2023.101257