An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions

Colonization of the gut and airways by pathogenic bacteria can lead to local tissue destruction and life-threatening systemic infections, especially in immunologically compromised individuals. Here, we describe an mRNA-based platform enabling delivery of pathogen-specific immunoglobulin A (IgA) mono...

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Detalles Bibliográficos
Autores principales: Deal, Cailin E., Richards, Angelene F., Yeung, Tracy, Maron, Max J., Wang, Ziqiu, Lai, Yen-Ting, Fritz, Brian R., Himansu, Sunny, Narayanan, Elisabeth, Liu, Ding, Koleva, Rositsa, Licht, Stuart, Hsiao, Chiaowen J., Rajlic, Ivana L., Koch, Hillary, Kleyman, Michael, Pulse, Mark E., Weiss, William J., Doering, Jennifer E., Lindberg, Samantha K., Mantis, Nicholas J., Carfi, Andrea, Plante, Obadiah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694625/
https://www.ncbi.nlm.nih.gov/pubmed/37918405
http://dx.doi.org/10.1016/j.xcrm.2023.101253

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