Prior antibiotic administration disrupts anti-PD-1 responses in advanced gastric cancer by altering the gut microbiome and systemic immune response

Evidence on whether prior antibiotic (pATB) administration modulates outcomes of programmed cell death protein-1 (PD-1) inhibitors in advanced gastric cancer (AGC) is scarce. In this study, we find that pATB administration is consistently associated with poor progression-free survival (PFS) and over...

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Detalles Bibliográficos
Autores principales: Kim, Chang Gon, Koh, June-Young, Shin, Su-Jin, Shin, Ji-Hee, Hong, Moonki, Chung, Hyun Cheol, Rha, Sun Young, Kim, Hyo Song, Lee, Choong-Kun, Lee, Ji Hyun, Han, Yejeong, Kim, Hyoyong, Che, Xiumei, Yun, Un-Jung, Kim, Hyunki, Kim, Jee Hung, Lee, Seo Young, Park, Su Kyoung, Park, Sejung, Kim, Hyunwook, Ahn, Jin Young, Jeung, Hei-Cheul, Lee, Jeong Seok, Nam, Young-Do, Jung, Minkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694627/
https://www.ncbi.nlm.nih.gov/pubmed/37890486
http://dx.doi.org/10.1016/j.xcrm.2023.101251

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