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The combined HPV16-E2/E6/E7 T cell response in oropharyngeal cancer predicts superior survival
Tumor-infiltrating HPV16-E2-specific CD8(+) T cells have been detected in HPV16-induced oropharyngeal squamous cell carcinoma (OPSCC). Whether intratumoral CD4(+) T cells target HPV16 E2 and if HPV16-E2-specific immunity contributes to better clinical outcome is unknown. In a prospective HPV16(+) OP...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694628/ https://www.ncbi.nlm.nih.gov/pubmed/37924817 http://dx.doi.org/10.1016/j.xcrm.2023.101262 |