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The combined HPV16-E2/E6/E7 T cell response in oropharyngeal cancer predicts superior survival

Tumor-infiltrating HPV16-E2-specific CD8(+) T cells have been detected in HPV16-induced oropharyngeal squamous cell carcinoma (OPSCC). Whether intratumoral CD4(+) T cells target HPV16 E2 and if HPV16-E2-specific immunity contributes to better clinical outcome is unknown. In a prospective HPV16(+) OP...

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Detalles Bibliográficos
Autores principales:	Santegoets, Saskia J., Stolk, Anouk, Welters, Marij J.P., van der Burg, Sjoerd H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694628/ https://www.ncbi.nlm.nih.gov/pubmed/37924817 http://dx.doi.org/10.1016/j.xcrm.2023.101262

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