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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

Internal tandem duplication mutations of the FMS-like tyrosine kinase-3 (FLT3-ITDs) occur in 25%–30% of patients with acute myeloid leukemia (AML) and are associated with dismal prognosis. Although FLT3 inhibitors have demonstrated initial clinical efficacy, the overall outcome of patients with FLT3...

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Detalles Bibliográficos
Autores principales:	Long, Jun, Chen, Xinjie, Shen, Yan, Lei, Yichen, Mu, Lili, Wang, Zhen, Xiang, Rufang, Gao, Wenhui, Wang, Lining, Wang, Ling, Jiang, Jieling, Zhang, Wenjun, Lu, Huina, Dong, Yan, Ding, Yi, Zhu, Honghu, Hong, Dengli, Sun, Yi Eve, Hu, Jiong, Liang, Aibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694671/ https://www.ncbi.nlm.nih.gov/pubmed/37951217 http://dx.doi.org/10.1016/j.xcrm.2023.101286

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