Dominant CD4(+) T cell receptors remain stable throughout antiretroviral therapy-mediated immune restoration in people with HIV

In people with HIV (PWH), the post-antiretroviral therapy (ART) window is critical for immune restoration and HIV reservoir stabilization. We employ deep immune profiling and T cell receptor (TCR) sequencing and examine proliferation to assess how ART impacts T cell homeostasis. In PWH on long-term...

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Detalles Bibliográficos
Autores principales: Sponaugle, Alexis, Weideman, Ann Marie K., Ranek, Jolene, Atassi, Gatphan, Kuruc, JoAnn, Adimora, Adaora A., Archin, Nancie M., Gay, Cynthia, Kuritzkes, Daniel R., Margolis, David M., Vincent, Benjamin G., Stanley, Natalie, Hudgens, Michael G., Eron, Joseph J., Goonetilleke, Nilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694675/
https://www.ncbi.nlm.nih.gov/pubmed/37949070
http://dx.doi.org/10.1016/j.xcrm.2023.101268

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