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Tipping the GVH/GVL balance by targeting HIF1α
Promoting GVL activity while eliminating GVHD is the utmost goal to treat hematological malignancies with allo-HCT. Bailey et al. demonstrate that targeting HIF1α can favor GVL activity while limiting GVHD after allo-HCT even in combination with immune checkpoint inhibition.(1)
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694739/ https://www.ncbi.nlm.nih.gov/pubmed/37992679 http://dx.doi.org/10.1016/j.xcrm.2023.101295 |