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The potential of patient-derived organoids in precision medicine of biliary tract cancer

Chemotherapy resistance in biliary tract cancer (BTC) presents a major clinical hurdle. Ren et al.(1) developed and characterized an extensive collection of BTC patient-derived organoid (PDO) models, enabling advanced investigation of chemotherapy response prediction.

Detalles Bibliográficos
Autores principales: Yáñez-Bartolomé, Mariana, Macarulla, Teresa, Tian, Tian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694744/
https://www.ncbi.nlm.nih.gov/pubmed/37992681
http://dx.doi.org/10.1016/j.xcrm.2023.101294
Descripción
Sumario:Chemotherapy resistance in biliary tract cancer (BTC) presents a major clinical hurdle. Ren et al.(1) developed and characterized an extensive collection of BTC patient-derived organoid (PDO) models, enabling advanced investigation of chemotherapy response prediction.