The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma

In this issue, Pang and colleagues(1) identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.

Detalles Bibliográficos
Autores principales: Mitchell, Jonathan, Colon, Bruno, Bayik, Defne, Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694751/
https://www.ncbi.nlm.nih.gov/pubmed/37992680
http://dx.doi.org/10.1016/j.xcrm.2023.101293
Descripción
Sumario:In this issue, Pang and colleagues(1) identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.

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