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The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma

In this issue, Pang and colleagues(1) identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.

Detalles Bibliográficos
Autores principales: Mitchell, Jonathan, Colon, Bruno, Bayik, Defne, Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694751/
https://www.ncbi.nlm.nih.gov/pubmed/37992680
http://dx.doi.org/10.1016/j.xcrm.2023.101293
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author Mitchell, Jonathan
Colon, Bruno
Bayik, Defne
Lathia, Justin D.
author_facet Mitchell, Jonathan
Colon, Bruno
Bayik, Defne
Lathia, Justin D.
author_sort Mitchell, Jonathan
collection PubMed
description In this issue, Pang and colleagues(1) identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.
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spelling pubmed-106947512023-12-05 The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma Mitchell, Jonathan Colon, Bruno Bayik, Defne Lathia, Justin D. Cell Rep Med Preview In this issue, Pang and colleagues(1) identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia. Elsevier 2023-11-21 /pmc/articles/PMC10694751/ /pubmed/37992680 http://dx.doi.org/10.1016/j.xcrm.2023.101293 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Mitchell, Jonathan
Colon, Bruno
Bayik, Defne
Lathia, Justin D.
The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title_full The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title_fullStr The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title_full_unstemmed The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title_short The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
title_sort missing link? lgmn connects hypoxia and immunosuppression in glioblastoma
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694751/
https://www.ncbi.nlm.nih.gov/pubmed/37992680
http://dx.doi.org/10.1016/j.xcrm.2023.101293
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