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GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells

Lack of targetable antigens is a key limitation for developing successful T cell-based immunotherapies. Members of the unfolded protein response (UPR) represent ideal immunotherapy targets because the UPR regulates the ability of cancer cells to resist cell death, sustain proliferation, and metastas...

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Detalles Bibliográficos
Autores principales:	Ibanez, Jorge, Hebbar, Nikhil, Thanekar, Unmesha, Yi, Zhongzhen, Houke, Haley, Ward, Meghan, Nevitt, Chris, Tian, Liqing, Mack, Stephen C., Sheppard, Heather, Chiang, Jason, Velasquez, M. Paulina, Krenciute, Giedre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694756/ https://www.ncbi.nlm.nih.gov/pubmed/37992682 http://dx.doi.org/10.1016/j.xcrm.2023.101297

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