Isatin-based benzyloxybenzene derivatives as monoamine oxidase inhibitors with neuroprotective effect targeting neurogenerative disease treatment

Eighteen isatin-based benzyloxybenzaldehyde derivatives from three subseries, ISB, ISFB, and ISBB, were synthesized and their ability to inhibit monoamine oxidase (MAO) was evaluated. The inhibitory activity of all synthesized compounds was found to be more profound against MAO-B than MAO-A. Compoun...

Descripción completa

Detalles Bibliográficos
Autores principales: Benny, Feba, Oh, Jong Min, Kumar, Sunil, Abdelgawad, Mohamed A., Ghoneim, Mohammed M., Abdel-Bakky, Mohamed Sadek, Kukerti, Neelima, Jose, Jobin, Kim, Hoon, Mathew, Bijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694828/
http://dx.doi.org/10.1039/d3ra07035b

Ejemplares similares

Ejemplares similares