Rotundic acid improves nonalcoholic steatohepatitis in mice by regulating glycolysis and the TLR4/AP1 signaling pathway

BACKGROUND: Steatosis and inflammation are the hallmarks of nonalcoholic steatohepatitis (NASH). Rotundic acid (RA) is among the key triterpenes of Ilicis Rotundae Cortex and has exhibited multipronged effects in terms of lowering the lipid content and alleviating inflammation. The study objective i...

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Detalles Bibliográficos
Autores principales: Shi, Xing-Yang, Zheng, Xiao-Min, Liu, Hui-Jie, Han, Xue, Zhang, Lei, Hu, Bei, Li, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694891/
http://dx.doi.org/10.1186/s12944-023-01976-z

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