hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma

BACKGROUND: Circular RNAs (circRNAs) play important roles in the occurrence and development of cancer and chemoresistance. DNA damage repair contributes to the proliferation of cancer cells and resistance to chemotherapy-induced apoptosis. However, the role of circRNAs in the regulation of DNA damag...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Ma, Xiao, Zhang, Xiuzhong, Zhang, Chong, Zhang, Yi, Gong, Shuai, Wu, Nai, Zhang, Peng, Feng, Xinyu, Guo, Jiaxuan, Zhao, Mengmeng, Ren, Zeqiang, Zhang, Pengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694898/
https://www.ncbi.nlm.nih.gov/pubmed/38044421
http://dx.doi.org/10.1186/s12943-023-01887-8

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