Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes

BACKGROUND: In vitro and in vivo studies have shown that certain cytokines and hormones may play a role in the development and progression of type 2 diabetes (T2D). However, studies on their role in T2D in humans are scarce. We evaluated associations between 11 circulating cytokines and hormones wit...

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Autores principales: Meeks, Karlijn A. C., Bentley, Amy R., Assimes, Themistocles L., Franceschini, Nora, Adeyemo, Adebowale A., Rotimi, Charles N., Doumatey, Ayo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694992/
https://www.ncbi.nlm.nih.gov/pubmed/38049854
http://dx.doi.org/10.1186/s13073-023-01263-7

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