Roles of Fatty Acid Chain Length and Enzyme-Oriented Drug Controlled Release from pH-Triggering Self-Assembled Fatty Acid Conjugated Quetiapine Nanosuspensions

BACKGROUND: Quetiapine (QTP) is a first-line antipsychotic drug, but its therapeutic druggability and patient adherence were limited due to high oral dose strength, low bioavailability and physicochemical/biopharmaceutical issues. PURPOSE: To investigate the roles of fatty acid chain length and enzy...

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Detalles Bibliográficos
Autores principales: Nguyen, Hy D, Ngo, Hai V, Nguyen, Van Hong, Gil, Myung-Chul, Lee, Beom-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695143/
http://dx.doi.org/10.2147/IJN.S440207

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