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Polyamines preferentially interact with bent adenine tracts in double-stranded DNA
Polyamines, such as putrescine, spermidine and spermine, have indirectly been linked with the regulation of gene expression, and their concentrations are typically increased in cancer cells. Although effects on transcription factor binding to cognate DNA targets have been demonstrated, the mechanism...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069516/ https://www.ncbi.nlm.nih.gov/pubmed/15788751 http://dx.doi.org/10.1093/nar/gki319 |