How to avoid intraoperative complications of active paragangliomas?

BACKGROUND: Paragangliomas (PGs) are very rare neuroendocrine tumors that can be found in unusual locations such as the spinal canal. Some PGs may be endocrinologically active, containing neurotransmitters such as noradrenaline, adrenaline, and serotonin. This can lead to unexpected neurotransmitter...

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Autores principales: Zekaj, Edvin, Callea, Marcella, Saleh, Christian, Iess, Guglielmo, Jaszczuk, Phillip, Steiner, Luzius A., Kenstaviciute, Viktorija, Servello, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695454/
http://dx.doi.org/10.25259/SNI_620_2023
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author Zekaj, Edvin
Callea, Marcella
Saleh, Christian
Iess, Guglielmo
Jaszczuk, Phillip
Steiner, Luzius A.
Kenstaviciute, Viktorija
Servello, Domenico
author_facet Zekaj, Edvin
Callea, Marcella
Saleh, Christian
Iess, Guglielmo
Jaszczuk, Phillip
Steiner, Luzius A.
Kenstaviciute, Viktorija
Servello, Domenico
author_sort Zekaj, Edvin
collection PubMed
description BACKGROUND: Paragangliomas (PGs) are very rare neuroendocrine tumors that can be found in unusual locations such as the spinal canal. Some PGs may be endocrinologically active, containing neurotransmitters such as noradrenaline, adrenaline, and serotonin. This can lead to unexpected neurotransmitter release during the removal of PGs, leading to a hypertensive crisis. CASE DESCRIPTION: We present two patients who underwent surgical removal of a secretory filum terminale PG. CONCLUSION: If laboratory tests are suggestive of a secretory tumor, surgery should include anesthesiologic preparation similar to cases of pheochromocytoma.
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spelling pubmed-106954542023-12-05 How to avoid intraoperative complications of active paragangliomas? Zekaj, Edvin Callea, Marcella Saleh, Christian Iess, Guglielmo Jaszczuk, Phillip Steiner, Luzius A. Kenstaviciute, Viktorija Servello, Domenico Surg Neurol Int Case Report BACKGROUND: Paragangliomas (PGs) are very rare neuroendocrine tumors that can be found in unusual locations such as the spinal canal. Some PGs may be endocrinologically active, containing neurotransmitters such as noradrenaline, adrenaline, and serotonin. This can lead to unexpected neurotransmitter release during the removal of PGs, leading to a hypertensive crisis. CASE DESCRIPTION: We present two patients who underwent surgical removal of a secretory filum terminale PG. CONCLUSION: If laboratory tests are suggestive of a secretory tumor, surgery should include anesthesiologic preparation similar to cases of pheochromocytoma. Scientific Scholar 2023-11-24 /pmc/articles/PMC10695454/ http://dx.doi.org/10.25259/SNI_620_2023 Text en Copyright: © 2023 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Zekaj, Edvin
Callea, Marcella
Saleh, Christian
Iess, Guglielmo
Jaszczuk, Phillip
Steiner, Luzius A.
Kenstaviciute, Viktorija
Servello, Domenico
How to avoid intraoperative complications of active paragangliomas?
title How to avoid intraoperative complications of active paragangliomas?
title_full How to avoid intraoperative complications of active paragangliomas?
title_fullStr How to avoid intraoperative complications of active paragangliomas?
title_full_unstemmed How to avoid intraoperative complications of active paragangliomas?
title_short How to avoid intraoperative complications of active paragangliomas?
title_sort how to avoid intraoperative complications of active paragangliomas?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695454/
http://dx.doi.org/10.25259/SNI_620_2023
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