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Perianal rhabdomyosarcoma in an adult: A case report and review of the literature
Perianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695526/ http://dx.doi.org/10.1097/MD.0000000000036276 |
_version_ | 1785153584721035264 |
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author | Yang, Ning Kong, Dexian Wang, Xv Liu, Yabin |
author_facet | Yang, Ning Kong, Dexian Wang, Xv Liu, Yabin |
author_sort | Yang, Ning |
collection | PubMed |
description | Perianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles. After 3 cycles of nivolumab, dacarbazine, cisplatin, and vinblastine therapy, a partial response was identified in the patient. The surgical resection was performed. The patient received neoadjuvant chemotherapy before surgery and was weak after surgery, so he did not receive chemoradiotherapy. The patient succumbed after 11 months postoperatively due to widespread intraabdominal metastasis. |
format | Online Article Text |
id | pubmed-10695526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-106955262023-12-05 Perianal rhabdomyosarcoma in an adult: A case report and review of the literature Yang, Ning Kong, Dexian Wang, Xv Liu, Yabin Medicine (Baltimore) 5700 Perianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles. After 3 cycles of nivolumab, dacarbazine, cisplatin, and vinblastine therapy, a partial response was identified in the patient. The surgical resection was performed. The patient received neoadjuvant chemotherapy before surgery and was weak after surgery, so he did not receive chemoradiotherapy. The patient succumbed after 11 months postoperatively due to widespread intraabdominal metastasis. Lippincott Williams & Wilkins 2023-12-01 /pmc/articles/PMC10695526/ http://dx.doi.org/10.1097/MD.0000000000036276 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. |
spellingShingle | 5700 Yang, Ning Kong, Dexian Wang, Xv Liu, Yabin Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title | Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title_full | Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title_fullStr | Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title_full_unstemmed | Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title_short | Perianal rhabdomyosarcoma in an adult: A case report and review of the literature |
title_sort | perianal rhabdomyosarcoma in an adult: a case report and review of the literature |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695526/ http://dx.doi.org/10.1097/MD.0000000000036276 |
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