Cargando…

A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature

BACKGROUND: Breast cancer is one of the most common type of cancers worldwide and remains a critical health issue. Although there are numerous treatment options for advanced metastatic breast cancer, the results are not satisfactory, particularly for triple-negative breast cancer. New treatment moda...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Ting-Ting, Pan, Xiao-Juan, Zuo, Xi-Meng, Shi, Xiao-Guang, Wang, Yu-Kun, Sun, Ping, Gao, Xiang, Feng, Xue, Gao, Shuang, Wang, Tang-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695577/
http://dx.doi.org/10.1097/MD.0000000000036297
_version_ 1785153596259565568
author Ge, Ting-Ting
Pan, Xiao-Juan
Zuo, Xi-Meng
Shi, Xiao-Guang
Wang, Yu-Kun
Sun, Ping
Gao, Xiang
Feng, Xue
Gao, Shuang
Wang, Tang-Shun
author_facet Ge, Ting-Ting
Pan, Xiao-Juan
Zuo, Xi-Meng
Shi, Xiao-Guang
Wang, Yu-Kun
Sun, Ping
Gao, Xiang
Feng, Xue
Gao, Shuang
Wang, Tang-Shun
author_sort Ge, Ting-Ting
collection PubMed
description BACKGROUND: Breast cancer is one of the most common type of cancers worldwide and remains a critical health issue. Although there are numerous treatment options for advanced metastatic breast cancer, the results are not satisfactory, particularly for triple-negative breast cancer. New treatment modalities need to be explored. CASE PRESENTATION: We present the case of a breast cancer patient with multiple metastases who achieved a good response and tolerance to the combination treatment of utidelone plus capecitabine. After being treated with 10 cycles of combined treatment, the patient is now in a good general condition with a progression-free survival time of 10 months. CONCLUSION: To our knowledge, this is the first report of utidelone plus capecitabine successfully treating a patient with heavily pretreated metastatic breast cancer. This combined treatment offers a new option for patients with multi-drug resistant breast cancer.
format Online
Article
Text
id pubmed-10695577
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-106955772023-12-05 A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature Ge, Ting-Ting Pan, Xiao-Juan Zuo, Xi-Meng Shi, Xiao-Guang Wang, Yu-Kun Sun, Ping Gao, Xiang Feng, Xue Gao, Shuang Wang, Tang-Shun Medicine (Baltimore) 5750 BACKGROUND: Breast cancer is one of the most common type of cancers worldwide and remains a critical health issue. Although there are numerous treatment options for advanced metastatic breast cancer, the results are not satisfactory, particularly for triple-negative breast cancer. New treatment modalities need to be explored. CASE PRESENTATION: We present the case of a breast cancer patient with multiple metastases who achieved a good response and tolerance to the combination treatment of utidelone plus capecitabine. After being treated with 10 cycles of combined treatment, the patient is now in a good general condition with a progression-free survival time of 10 months. CONCLUSION: To our knowledge, this is the first report of utidelone plus capecitabine successfully treating a patient with heavily pretreated metastatic breast cancer. This combined treatment offers a new option for patients with multi-drug resistant breast cancer. Lippincott Williams & Wilkins 2023-12-01 /pmc/articles/PMC10695577/ http://dx.doi.org/10.1097/MD.0000000000036297 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5750
Ge, Ting-Ting
Pan, Xiao-Juan
Zuo, Xi-Meng
Shi, Xiao-Guang
Wang, Yu-Kun
Sun, Ping
Gao, Xiang
Feng, Xue
Gao, Shuang
Wang, Tang-Shun
A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title_full A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title_fullStr A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title_full_unstemmed A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title_short A new strategy for the treatment of heavily pretreated metastatic breast cancer: A case report and review of the literature
title_sort new strategy for the treatment of heavily pretreated metastatic breast cancer: a case report and review of the literature
topic 5750
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695577/
http://dx.doi.org/10.1097/MD.0000000000036297
work_keys_str_mv AT getingting anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT panxiaojuan anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT zuoximeng anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT shixiaoguang anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT wangyukun anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT sunping anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT gaoxiang anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT fengxue anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT gaoshuang anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT wangtangshun anewstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT getingting newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT panxiaojuan newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT zuoximeng newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT shixiaoguang newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT wangyukun newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT sunping newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT gaoxiang newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT fengxue newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT gaoshuang newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature
AT wangtangshun newstrategyforthetreatmentofheavilypretreatedmetastaticbreastcanceracasereportandreviewoftheliterature