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A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study

Severe sharp angular kyphosis resulting from Pott’s disease typically necessitates surgical intervention. The deployment of three-column osteotomy within the lesion and apical regions has been validated as an effective modality for the amelioration of angular kyphosis. Nonetheless, a propensity for...

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Autores principales: Zhao, Deng, Wang, Fei, Hu, Zhengjun, Zhong, Rui, Huang, Huaqiang, Zhang, Zhong, Jiang, Dengxu, Liang, Yan, Liang, Yijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695937/
https://www.ncbi.nlm.nih.gov/pubmed/38049473
http://dx.doi.org/10.1038/s41598-023-48891-y
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author Zhao, Deng
Wang, Fei
Hu, Zhengjun
Zhong, Rui
Huang, Huaqiang
Zhang, Zhong
Jiang, Dengxu
Liang, Yan
Liang, Yijian
author_facet Zhao, Deng
Wang, Fei
Hu, Zhengjun
Zhong, Rui
Huang, Huaqiang
Zhang, Zhong
Jiang, Dengxu
Liang, Yan
Liang, Yijian
author_sort Zhao, Deng
collection PubMed
description Severe sharp angular kyphosis resulting from Pott’s disease typically necessitates surgical intervention. The deployment of three-column osteotomy within the lesion and apical regions has been validated as an effective modality for the amelioration of angular kyphosis. Nonetheless, a propensity for residual kyphosis persists, accompanied by a significant perioperative risk profile. In pursuit of optimizing correctional outcomes and diminishing complication rates, we proposed an innovative surgical approach, utilizing osteotomy in the non-lesioned zones for the rectification of severe angular kyphosis associated with Pott’s disease. This retrospective investigation encompasses 16 subjects who underwent this novel surgical tactic, involving osteotomies in non-lesioned vertebral segments, at our institution from 2016 to 2018. Radiographic measures, encompassing kyphotic angle and sagittal vertical axis (SVA), were documented at baseline and during terminal follow-up. Neurological status was evaluated via the American Spinal Injury Association (ASIA) grading system. Operative duration, volume of hemorrhage, and perioperative complications were systematically recorded. The cohort included 6 males and 10 females with an average age of 30.7 ± 11.41 years. Follow-up intervals spanned 24 to 42 months. Mean operative time and blood loss were 492 ± 127.3 min and 1791 ± 788.8 ml, respectively. The kyphotic angle improved from 97.6 ± 14.6° to 28.8 ± 18.70°. In cases with lumbar afflictions, vertebral restoration was achieved (L1–L5 and L2–S1). Initial mean SVA of 6.7 ± 3.58 cm was reduced to 3.3 ± 1.57 cm at follow-up. Neurological function enhancement was observed in six patients, while ten maintained baseline status. Complication rates, including wound infection and rod fracture at 12 months, were observed in approximately 11.8% of cases. Our findings suggest that the surgical strategy is both effective and safe for addressing severe angular kyphosis due to Pott’s disease, contingent upon the expertise of the surgical unit.
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spelling pubmed-106959372023-12-06 A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study Zhao, Deng Wang, Fei Hu, Zhengjun Zhong, Rui Huang, Huaqiang Zhang, Zhong Jiang, Dengxu Liang, Yan Liang, Yijian Sci Rep Article Severe sharp angular kyphosis resulting from Pott’s disease typically necessitates surgical intervention. The deployment of three-column osteotomy within the lesion and apical regions has been validated as an effective modality for the amelioration of angular kyphosis. Nonetheless, a propensity for residual kyphosis persists, accompanied by a significant perioperative risk profile. In pursuit of optimizing correctional outcomes and diminishing complication rates, we proposed an innovative surgical approach, utilizing osteotomy in the non-lesioned zones for the rectification of severe angular kyphosis associated with Pott’s disease. This retrospective investigation encompasses 16 subjects who underwent this novel surgical tactic, involving osteotomies in non-lesioned vertebral segments, at our institution from 2016 to 2018. Radiographic measures, encompassing kyphotic angle and sagittal vertical axis (SVA), were documented at baseline and during terminal follow-up. Neurological status was evaluated via the American Spinal Injury Association (ASIA) grading system. Operative duration, volume of hemorrhage, and perioperative complications were systematically recorded. The cohort included 6 males and 10 females with an average age of 30.7 ± 11.41 years. Follow-up intervals spanned 24 to 42 months. Mean operative time and blood loss were 492 ± 127.3 min and 1791 ± 788.8 ml, respectively. The kyphotic angle improved from 97.6 ± 14.6° to 28.8 ± 18.70°. In cases with lumbar afflictions, vertebral restoration was achieved (L1–L5 and L2–S1). Initial mean SVA of 6.7 ± 3.58 cm was reduced to 3.3 ± 1.57 cm at follow-up. Neurological function enhancement was observed in six patients, while ten maintained baseline status. Complication rates, including wound infection and rod fracture at 12 months, were observed in approximately 11.8% of cases. Our findings suggest that the surgical strategy is both effective and safe for addressing severe angular kyphosis due to Pott’s disease, contingent upon the expertise of the surgical unit. Nature Publishing Group UK 2023-12-04 /pmc/articles/PMC10695937/ /pubmed/38049473 http://dx.doi.org/10.1038/s41598-023-48891-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhao, Deng
Wang, Fei
Hu, Zhengjun
Zhong, Rui
Huang, Huaqiang
Zhang, Zhong
Jiang, Dengxu
Liang, Yan
Liang, Yijian
A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title_full A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title_fullStr A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title_full_unstemmed A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title_short A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
title_sort novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to pott’s disease: a retrospectively study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695937/
https://www.ncbi.nlm.nih.gov/pubmed/38049473
http://dx.doi.org/10.1038/s41598-023-48891-y
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