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Effectiveness of VSV vectored SARS-CoV-2 spike when administered through intranasal, intramuscular or a combination of both

A critical feature of the VSV vector platform is the ability to pseudotype the virus with different glycoproteins from other viruses, thus altering cellular tropism of the recombinant virus. The route of administration is critical in triggering local and systemic immune response and protection. Most...

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Detalles Bibliográficos
Autores principales: Beitari, Saina, Agbayani, Gerard, Hewitt, Melissa, Duque, Diana, Bavananthasivam, Jegarubee, Sandhu, Jagdeep K., Akache, Bassel, Hadžisejdić, Ita, Tran, Anh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695950/
https://www.ncbi.nlm.nih.gov/pubmed/38049498
http://dx.doi.org/10.1038/s41598-023-48397-7

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