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Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin

This study aimed to test the efficacy of different silica-based toothpastes with or without chitosan, as a method of cleaning the acrylic surfaces of denture prostheses. Acrylic resin specimens were prepared to evaluate surface roughness and gloss (n = 10), and Candida albicans adhesion/inhibition (...

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Autores principales: Varaschin Theodorovicz, Kaye, Vieira-Junior, Waldemir Franscisco, Manoel Garcia, Raissa, Pini Simões Gobbi, Ludmila, Mayume Mori, Mariana, Prado Dias Filho, Benedito, Alves Nunes Leite Lima, Débora, Sundfeld, Daniel, Pavesi Pini, Núbia Inocencya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696081/
https://www.ncbi.nlm.nih.gov/pubmed/38049493
http://dx.doi.org/10.1038/s41598-023-47530-w
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author Varaschin Theodorovicz, Kaye
Vieira-Junior, Waldemir Franscisco
Manoel Garcia, Raissa
Pini Simões Gobbi, Ludmila
Mayume Mori, Mariana
Prado Dias Filho, Benedito
Alves Nunes Leite Lima, Débora
Sundfeld, Daniel
Pavesi Pini, Núbia Inocencya
author_facet Varaschin Theodorovicz, Kaye
Vieira-Junior, Waldemir Franscisco
Manoel Garcia, Raissa
Pini Simões Gobbi, Ludmila
Mayume Mori, Mariana
Prado Dias Filho, Benedito
Alves Nunes Leite Lima, Débora
Sundfeld, Daniel
Pavesi Pini, Núbia Inocencya
author_sort Varaschin Theodorovicz, Kaye
collection PubMed
description This study aimed to test the efficacy of different silica-based toothpastes with or without chitosan, as a method of cleaning the acrylic surfaces of denture prostheses. Acrylic resin specimens were prepared to evaluate surface roughness and gloss (n = 10), and Candida albicans adhesion/inhibition (n = 2). Two toothpastes with different degrees of abrasiveness were used: Colgate (CT) and Elmex (EX), with or without 0.5% chitosan (Ch) microparticles (CTCh or EXCh, respectively). The negative control was brushed with distilled water. Brushing was simulated with a machine. Surface roughness and gloss were analyzed before and after brushing. Candida albicans incidence/inhibition was tested qualitatively to determine the acrylic resin antifungal activity. The roughness and gloss data were analyzed with a generalized linear model, and the Kruskal Wallis and Dunn tests, respectively (α = 5%). Brushing with toothpastes increased roughness and reduced gloss, compared with the negative control (p < 0.05). CT showed a more significantly different change in roughness and gloss, in relation to the other groups (p < 0.05). Addition of chitosan to CT reduced its abrasive potential, and yielded results similar to those of EX and EXCh. Specimens brushed with CT showed a higher potential for Candida albicans adherence, despite its higher antifungal action. Addition of chitosan to the toothpaste made both toothpaste and brushing more effective in inhibiting Candida albicans. CT had the potential to increase roughness, reduce gloss, and increase Candida albicans adherence. In contrast, chitosan added to CT showed greater antifungal potential, and a higher synergistic effect than EX.
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spelling pubmed-106960812023-12-06 Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin Varaschin Theodorovicz, Kaye Vieira-Junior, Waldemir Franscisco Manoel Garcia, Raissa Pini Simões Gobbi, Ludmila Mayume Mori, Mariana Prado Dias Filho, Benedito Alves Nunes Leite Lima, Débora Sundfeld, Daniel Pavesi Pini, Núbia Inocencya Sci Rep Article This study aimed to test the efficacy of different silica-based toothpastes with or without chitosan, as a method of cleaning the acrylic surfaces of denture prostheses. Acrylic resin specimens were prepared to evaluate surface roughness and gloss (n = 10), and Candida albicans adhesion/inhibition (n = 2). Two toothpastes with different degrees of abrasiveness were used: Colgate (CT) and Elmex (EX), with or without 0.5% chitosan (Ch) microparticles (CTCh or EXCh, respectively). The negative control was brushed with distilled water. Brushing was simulated with a machine. Surface roughness and gloss were analyzed before and after brushing. Candida albicans incidence/inhibition was tested qualitatively to determine the acrylic resin antifungal activity. The roughness and gloss data were analyzed with a generalized linear model, and the Kruskal Wallis and Dunn tests, respectively (α = 5%). Brushing with toothpastes increased roughness and reduced gloss, compared with the negative control (p < 0.05). CT showed a more significantly different change in roughness and gloss, in relation to the other groups (p < 0.05). Addition of chitosan to CT reduced its abrasive potential, and yielded results similar to those of EX and EXCh. Specimens brushed with CT showed a higher potential for Candida albicans adherence, despite its higher antifungal action. Addition of chitosan to the toothpaste made both toothpaste and brushing more effective in inhibiting Candida albicans. CT had the potential to increase roughness, reduce gloss, and increase Candida albicans adherence. In contrast, chitosan added to CT showed greater antifungal potential, and a higher synergistic effect than EX. Nature Publishing Group UK 2023-12-04 /pmc/articles/PMC10696081/ /pubmed/38049493 http://dx.doi.org/10.1038/s41598-023-47530-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Varaschin Theodorovicz, Kaye
Vieira-Junior, Waldemir Franscisco
Manoel Garcia, Raissa
Pini Simões Gobbi, Ludmila
Mayume Mori, Mariana
Prado Dias Filho, Benedito
Alves Nunes Leite Lima, Débora
Sundfeld, Daniel
Pavesi Pini, Núbia Inocencya
Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title_full Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title_fullStr Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title_full_unstemmed Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title_short Impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
title_sort impact of chitosan-incorporated toothpaste on roughness, gloss, and antifungal potential of acrylic resin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696081/
https://www.ncbi.nlm.nih.gov/pubmed/38049493
http://dx.doi.org/10.1038/s41598-023-47530-w
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