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ASC/inflammasome-independent pyroptosis in ovarian cancer cells through translational augmentation of caspase-1

Canonical pyroptosis is type of programmed cell death depending on active caspase-1, and the inflammasome carries out caspase-1 activation. Here, we showed that docosahexaenoic acid (DHA) induced ovarian cancer cell deaths in caspase-1-dependent manner. DHA increased caspase-1 activity and led to in...

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Detalles Bibliográficos
Autores principales: Calbay, Ozlem, Padia, Ravi, Akter, Mahmuda, Sun, Lei, Li, Bin, Qian, Nicole, Guo, Jianhui, Fu, Zheng, Jin, Lingtao, Huang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696124/
http://dx.doi.org/10.1016/j.isci.2023.108408