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Targeting polycomb repressor complex 2‐mediated bivalent promoter epigenetic silencing of secreted frizzled‐related protein 1 inhibits cholangiocarcinoma progression

BACKGROUND: Cholangiocarcinoma (CCA) refers to a collection of malignancies that are associated with a dismal prognosis. Currently, surgical resection is the only way to cure patients with CCA. Available systemic therapy is limited to gemcitabine plus cisplatin; however, this treatment is palliative...

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Detalles Bibliográficos
Autores principales:	Wu, Guanhua, Wang, Qi, Wang, Da, Xiong, Fei, Liu, Wenzheng, Chen, Junsheng, Wang, Bing, Huang, Wenhua, Wang, Xin, Chen, Yongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696163/ http://dx.doi.org/10.1002/ctm2.1502

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