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Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event

Medulloblastoma accounts for nearly 10% of childhood primary central nervous system (CNS) malignancies. However, it is rare in adults. Extracranial metastasis is commonly documented to involve bones but rarely involves lymph nodes. Herein, we present an unusual case of primary CNS medulloblastoma in...

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Autores principales: Elsayed, Afnan, Alardati, Hosam, Al-Maghrabi, Jaudah, Meliti, Abdelrazak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696280/
http://dx.doi.org/10.7759/cureus.48301
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author Elsayed, Afnan
Alardati, Hosam
Al-Maghrabi, Jaudah
Meliti, Abdelrazak
author_facet Elsayed, Afnan
Alardati, Hosam
Al-Maghrabi, Jaudah
Meliti, Abdelrazak
author_sort Elsayed, Afnan
collection PubMed
description Medulloblastoma accounts for nearly 10% of childhood primary central nervous system (CNS) malignancies. However, it is rare in adults. Extracranial metastasis is commonly documented to involve bones but rarely involves lymph nodes. Herein, we present an unusual case of primary CNS medulloblastoma in an adult patient with extracranial metastasis to a lymph node, which exhibits a myogenic differentiation. To the best of our knowledge, this is the fourth reported case of medulloblastoma in an adult with extracranial metastasis to the lymph node and the first reported case of extracranial metastatic medulloblastoma with myogenic differentiation that involves a lymph node.
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spelling pubmed-106962802023-12-06 Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event Elsayed, Afnan Alardati, Hosam Al-Maghrabi, Jaudah Meliti, Abdelrazak Cureus Neurosurgery Medulloblastoma accounts for nearly 10% of childhood primary central nervous system (CNS) malignancies. However, it is rare in adults. Extracranial metastasis is commonly documented to involve bones but rarely involves lymph nodes. Herein, we present an unusual case of primary CNS medulloblastoma in an adult patient with extracranial metastasis to a lymph node, which exhibits a myogenic differentiation. To the best of our knowledge, this is the fourth reported case of medulloblastoma in an adult with extracranial metastasis to the lymph node and the first reported case of extracranial metastatic medulloblastoma with myogenic differentiation that involves a lymph node. Cureus 2023-11-05 /pmc/articles/PMC10696280/ http://dx.doi.org/10.7759/cureus.48301 Text en Copyright © 2023, Elsayed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Elsayed, Afnan
Alardati, Hosam
Al-Maghrabi, Jaudah
Meliti, Abdelrazak
Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title_full Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title_fullStr Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title_full_unstemmed Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title_short Extracranial Medulloblastoma With Myogenic Differentiation: Report of a Rare Event
title_sort extracranial medulloblastoma with myogenic differentiation: report of a rare event
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696280/
http://dx.doi.org/10.7759/cureus.48301
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