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Development of risk prediction scores for diabetic peripheral neuropathy patients

OBJECTIVES: Risk prediction scores are important for early diagnosis and treatment of diseases. Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes, but the early diagnosis is challenging. This study developed a risk prediction model for DPN based on modifiable risk fact...

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Detalles Bibliográficos
Autores principales: Laxmi, Mathukumalli Sai, Prabhakar, Orsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696327/
http://dx.doi.org/10.25259/JNRP_151_2023
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author Laxmi, Mathukumalli Sai
Prabhakar, Orsu
author_facet Laxmi, Mathukumalli Sai
Prabhakar, Orsu
author_sort Laxmi, Mathukumalli Sai
collection PubMed
description OBJECTIVES: Risk prediction scores are important for early diagnosis and treatment of diseases. Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes, but the early diagnosis is challenging. This study developed a risk prediction model for DPN based on modifiable risk factors. MATERIALS AND METHODS: The study included 315 type 2 diabetes patients with and without DPN. Demographic, biochemical, and diagnostic data were collected. Multinomial logistic regression analysis was used to identify independent risk factors for DPN. RESULTS: Hemoglobin% and total red blood cells were identified as independent risk factors for DPN, used to develop a risk prediction score. CONCLUSION: The risk prediction score developed in this study can be used by physicians to quickly assess a patient’s risk of DPN and select appropriate therapeutic options. Routine monitoring of modifiable risk factors can improve DPN prognosis. Patients stratified by risk scores can better understand their risk and seek appropriate care.
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spelling pubmed-106963272023-12-06 Development of risk prediction scores for diabetic peripheral neuropathy patients Laxmi, Mathukumalli Sai Prabhakar, Orsu J Neurosci Rural Pract Original Article OBJECTIVES: Risk prediction scores are important for early diagnosis and treatment of diseases. Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes, but the early diagnosis is challenging. This study developed a risk prediction model for DPN based on modifiable risk factors. MATERIALS AND METHODS: The study included 315 type 2 diabetes patients with and without DPN. Demographic, biochemical, and diagnostic data were collected. Multinomial logistic regression analysis was used to identify independent risk factors for DPN. RESULTS: Hemoglobin% and total red blood cells were identified as independent risk factors for DPN, used to develop a risk prediction score. CONCLUSION: The risk prediction score developed in this study can be used by physicians to quickly assess a patient’s risk of DPN and select appropriate therapeutic options. Routine monitoring of modifiable risk factors can improve DPN prognosis. Patients stratified by risk scores can better understand their risk and seek appropriate care. Scientific Scholar 2023-11-10 2023 /pmc/articles/PMC10696327/ http://dx.doi.org/10.25259/JNRP_151_2023 Text en © 2023 Published by Scientific Scholar on behalf of Journal of Neurosciences in Rural Practice https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Laxmi, Mathukumalli Sai
Prabhakar, Orsu
Development of risk prediction scores for diabetic peripheral neuropathy patients
title Development of risk prediction scores for diabetic peripheral neuropathy patients
title_full Development of risk prediction scores for diabetic peripheral neuropathy patients
title_fullStr Development of risk prediction scores for diabetic peripheral neuropathy patients
title_full_unstemmed Development of risk prediction scores for diabetic peripheral neuropathy patients
title_short Development of risk prediction scores for diabetic peripheral neuropathy patients
title_sort development of risk prediction scores for diabetic peripheral neuropathy patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696327/
http://dx.doi.org/10.25259/JNRP_151_2023
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