Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin–Mediated Mitophagy

BACKGROUND & AIMS: Hepatic ischemia-reperfusion injury is a significant complication of partial hepatic resection and liver transplantation, impacting the prognosis of patients undergoing liver surgery. The protein proprotein convertase subtilisin/kexin type 9 (PCSK9) is primarily synthesized by...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Wang, Ziyi, Jia, Chenyang, Yu, Wenjie, Li, Xiangdong, Xia, Nan, Nie, Huiling, Wikana, Likalamu Pascalia, Chen, Minhao, Ni, Yong, Han, Sheng, Pu, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696400/
http://dx.doi.org/10.1016/j.jcmgh.2023.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696400/
http://dx.doi.org/10.1016/j.jcmgh.2023.09.004

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