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Brain apolipoprotein E levels in mice challenged by a Western diet increase in an allele-dependent manner

Human apolipoprotein E (APOE) is the greatest determinant of genetic risk for memory deficits and Alzheimer’s disease (AD). While APOE4 drives memory loss and high AD risk, APOE2 leads to healthy brain aging and reduced AD risk compared to the common APOE3 variant. We examined brain APOE protein lev...

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Detalles Bibliográficos
Autores principales:	Liemisa, Braison, Newbury, Samantha F., Novy, Mariah J., Pasato, Jonathan A., Morales-Corraliza, Jose, Peng, Katherine Y., Mathews, Paul M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696459/ http://dx.doi.org/10.1016/j.nbas.2023.100102

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