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Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease

IMPORTANCE: Nonmotor symptoms of Parkinson disease (PD) often predate the movement disorder by decades. Currently, there is no blood biomarker to define this prodromal phase. OBJECTIVE: To investigate whether α-synuclein in neuronally derived serum-extracellular vesicles identifies individuals at ri...

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Detalles Bibliográficos
Autores principales:	Yan, Shijun, Jiang, Cheng, Janzen, Annette, Barber, Thomas R., Seger, Aline, Sommerauer, Michael, Davis, Jason J., Marek, Kenneth, Hu, Michele T., Oertel, Wolfgang H., Tofaris, George K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696516/ https://www.ncbi.nlm.nih.gov/pubmed/38048087 http://dx.doi.org/10.1001/jamaneurol.2023.4398

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