Shotgun Proteomic-Based Approach with a Q-Exactive Hybrid Quadrupole-Orbitrap High-Resolution Mass Spectrometer for Protein Adductomics on a 3D Human Brain Tumor Neurospheroid Culture Model: The Identification of Adduct Formation in Calmodulin-Dependent Protein Kinase-2 and Annexin-A1 Induced by Pesticide Mixture

[Image: see text] Pesticides are increasingly used in combinations in crop protection, resulting in enhanced toxicities for various organisms. Although protein adductomics is challenging, it remains a powerful bioanalytical tool to check environmental exposure and characterize xenobiotic adducts as...

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Detalles Bibliográficos
Autores principales: Louati, Kaouthar, Maalej, Amina, Kolsi, Fatma, Kallel, Rim, Gdoura, Yassine, Borni, Mahdi, Hakim, Leila Sellami, Zribi, Rania, Choura, Sirine, Sayadi, Sami, Chamkha, Mohamed, Mnif, Basma, Khemakhem, Zouheir, Boudawara, Tahya Sellami, Boudawara, Mohamed Zaher, Safta, Fathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696604/
https://www.ncbi.nlm.nih.gov/pubmed/37906427
http://dx.doi.org/10.1021/acs.jproteome.3c00484

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