A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a highly debilitating neurodegenerative condition. Despite recent advancements in understanding the molecular mechanisms underlying ALS, there have been no significant improvements in therapeutic options for ALS patients in recent years. Currently,...

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Detalles Bibliográficos
Autores principales: Lombardo, Flavia L., Spila Alegiani, Stefania, Mayer, Flavia, Cipriani, Marta, Lo Giudice, Maria, Ludolph, Albert Christian, McDermott, Christopher J., Corcia, Philippe, Van Damme, Philip, Van den Berg, Leonard H., Hardiman, Orla, Nicolini, Gabriele, Vanacore, Nicola, Dickie, Brian, Albanese, Alberto, Puopolo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696667/
http://dx.doi.org/10.1186/s13063-023-07638-w

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