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Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

BACKGROUND: Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration of tacrolimus (TCR) at steady state increased after intravenous MTX administrat...

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Detalles Bibliográficos
Autores principales: Inoue, Chiaki, Yamamoto, Takehito, Miyata, Hiroshi, Suzuki, Hiroshi, Takada, Tappei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696830/
https://www.ncbi.nlm.nih.gov/pubmed/38049906
http://dx.doi.org/10.1186/s40780-023-00306-w

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