FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6

BACKGROUND: Disruption of the BBB is a harmful event after intracranial hemorrhage (ICH), and this disruption contributes to a series of secondary injuries. We hypothesized that FGF21 may have protective effects after intracranial hemorrhage (ICH) and investigated possible underlying molecular mecha...

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Detalles Bibliográficos
Autores principales: Wang, Runfeng, Wang, Jin, Zhang, Zhiguo, Ma, Bo, Sun, Shukai, Gao, Li, Gao, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696847/
https://www.ncbi.nlm.nih.gov/pubmed/38049769
http://dx.doi.org/10.1186/s10020-023-00755-x

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