Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

BACKGROUND: Lung neuroendocrine neoplasms (LungNENs) comprise a heterogeneous group of tumors ranging from indolent lesions with good prognosis to highly aggressive cancers. Carcinoids are the rarest LungNENs, display low to intermediate malignancy and may be surgically managed, but show resistance...

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Detalles Bibliográficos
Autores principales: Blázquez-Encinas, Ricardo, García-Vioque, Víctor, Caro-Cuenca, Teresa, Moreno-Montilla, María Trinidad, Mangili, Federica, Alors-Pérez, Emilia, Ventura, Sebastian, Herrera-Martínez, Aura D., Moreno-Casado, Paula, Calzado, Marco A., Salvatierra, Ángel, Gálvez-Moreno, María A., Fernandez-Cuesta, Lynnette, Foll, Matthieu, Luque, Raúl M., Alcala, Nicolas, Pedraza-Arevalo, Sergio, Ibáñez-Costa, Alejandro, Castaño, Justo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696873/
https://www.ncbi.nlm.nih.gov/pubmed/38049848
http://dx.doi.org/10.1186/s12967-023-04754-8

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