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Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks

BACKGROUND: Transcription factors regulate gene expression by binding to transcription factor binding sites (TFBSs). Most models for predicting TFBSs are based on position weight matrices (PWMs), which require a specific motif to be present in the DNA sequence and do not consider interdependencies o...

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Detalles Bibliográficos
Autores principales:	Proft, Sebastian, Leiz, Janna, Heinemann, Udo, Seelow, Dominik, Schmidt-Ott, Kai M., Rutkiewicz, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696883/ https://www.ncbi.nlm.nih.gov/pubmed/38049725 http://dx.doi.org/10.1186/s12864-023-09830-3

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