Cargando…

Introducing a novel chemotherapeutic drug formulated with anthraflavic acid for treating human breast carcinoma and type 2 diabetes mellitus

INTRODUCTION: Molecular docking as a versatile theoretical method was used to investigate the biological activities of anthraflavic acid in the presence of α-amylase. The outcomes revealed that anthraflavic acid has a considerable binding affinity to the enzyme with a docking score of –7.913 kcal/mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Gang, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Wainwright, Milton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2021
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696992/ http://dx.doi.org/10.5114/aoms/141173

Ejemplares similares

Optimization of extraction and quantification of Flavonoids from Averrhoa bilimbi fruits using RP-HPLC and its correlation between total flavonoids content against antimicrobial activity
por: Chau, Tan Phat, et al.
Publicado: (2021)

Attenuation of STAT3 Signaling Cascade by Daidzin Can Enhance the Apoptotic Potential of Bortezomib against Multiple Myeloma
por: Yang, Min Hee, et al.
Publicado: (2019)

Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
por: Hu, Xinglong, et al.
Publicado: (2021)

Histone deacetylase inhibitor pre-treatment enhances the efficacy of DNA-interacting chemotherapeutic drugs in gastric cancer
por: Amnekar, Ramchandra Vigay, et al.
Publicado: (2020)

The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells
por: Lee, Jong Hyun, et al.
Publicado: (2019)

3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma
por: Mohan, Chakrabhavi Dhananjaya, et al.
Publicado: (2021)

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells
por: Somu, Chaithanya, et al.
Publicado: (2020)

How to Simplify the Evaluation of Newly Introduced Chemotherapeutic Interventions in Myeloma
por: Morris, Treen Carson Michael, et al.
Publicado: (2021)

The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors
por: Charbonneau, Martine, et al.
Publicado: (2023)

Equisetum arvense L aqueous extract: a novel chemotherapeutic supplement for treatment of human colon carcinoma
por: Wang, Lei, et al.
Publicado: (2021)

Assessment of the bacterial contamination of hand air dryer in washrooms
por: Alharbi, Sulaiman Ali, et al.
Publicado: (2016)

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance
por: Monisha, Javadi, et al.
Publicado: (2018)

Self-Assembled Nanomicellar Formulation of Docetaxel as a Potential Breast Cancer Chemotherapeutic System
por: Alshamrani, Meshal, et al.
Publicado: (2022)

Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis
por: Shanmugam, Muthu K., et al.
Publicado: (2018)

Use of Targeted Liposome-based Chemotherapeutics to Treat Breast Cancer
por: Khan, David R, et al.
Publicado: (2015)

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway
por: Mohan, Chakrabhavi Dhananjaya, et al.
Publicado: (2018)

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma
por: Lee, Jong Hyun, et al.
Publicado: (2020)

Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Regulating the STAT3 Signaling Pathway
por: Arora, Loukik, et al.
Publicado: (2021)

Presentation of the Molecular Subtypes of Breast Cancer Detected By Immunohistochemistry in Surgically Treated Patients
por: Kondov, Borislav, et al.
Publicado: (2018)

An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect
por: Fraga-Silva, Rodrigo Araujo, et al.
Publicado: (2011)

Patterns of pretreatment drug resistance mutations of very early diagnosed and treated infants in Botswana
por: Moraka, Natasha Onalenna, et al.
Publicado: (2021)

Thrombogenicity of flow diverters in an ex vivo shunt model: effect of phosphorylcholine surface modification
por: Hagen, Matthew W, et al.
Publicado: (2017)

The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer
por: Dakir, EL-Habib, et al.
Publicado: (2018)

3449 Bacterial biotransformation of chemotherapeutics may promote diversity among the intestinal microbiota
por: Blaustein, Ryan Andrew, et al.
Publicado: (2019)

Deep Learning Mechanism for Predicting the Axillary Lymph Node Metastasis in Patients with Primary Breast Cancer
por: Ashokkumar, N., et al.
Publicado: (2022)

Solid lipid nanoparticles delivering anti-inflammatory drugs to treat inflammatory bowel disease: Effects in an in vivo model
por: Dianzani, Chiara, et al.
Publicado: (2017)

BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism
por: Li, Xiao-Hua, et al.
Publicado: (2023)

Mycelium of fungi isolated from mouldy foods inhibits Staphylococcus aureus including MRSA – A rationale for the re-introduction of mycotherapy?
por: Alnaimat, Sulaiman, et al.
Publicado: (2015)

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations
por: Manikandan, S
Publicado: (2012)

The Therapeutic Potential of Conditioned Medium from Human Breast Milk Stem Cells in Treating Spinal Cord Injury
por: Borhani-Haghighi, Maryam, et al.
Publicado: (2020)

Multiphysics and Multiscale Analysis for Chemotherapeutic Drug
por: Zhang, Linan, et al.
Publicado: (2015)

Role of chemotherapeutic drugs in immunomodulation of cancer
por: Mukherjee, Oishi, et al.
Publicado: (2023)

Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model
por: Girardi, Bruna, et al.
Publicado: (2020)

Antinociceptive and anti-inflammatory activities of butein in different nociceptive and inflammatory mice models
por: Gao, Li, et al.
Publicado: (2021)

Drug–Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics
por: Buchtova, Tereza, et al.
Publicado: (2023)

Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations
por: Abdel-Rahman, Wael M, et al.
Publicado: (2017)

Implications for Ophthalmic Formulations: Ocular Buffers Show Varied Cytotoxic Impact on Human Corneal–Limbal and Human Conjunctival Epithelial Cells
por: Schuerer, Nadine, et al.
Publicado: (2017)

2145 Drug formulation strategies: A vital but nearly invisible component in translational education
por: MacArthur, Robert B., et al.
Publicado: (2018)

CRP Gene Polymorphism and Their Risk Association With Type 2 Diabetes Mellitus
por: Jebur, Hakim Bahlok, et al.
Publicado: (2018)

Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
por: Samuel, Temesgen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6e94muhmfkmhi5mvs5laf8l80k