Design of stimulus-responsive two-state hinge proteins

In nature, proteins that switch between two conformations in response to environmental stimuli structurally transduce biochemical information in a manner analogous to how transistors control information flow in computing devices. Designing proteins with two distinct but fully structured conformation...

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Detalles Bibliográficos
Autores principales: Praetorius, Florian, Leung, Philip J. Y., Tessmer, Maxx H., Broerman, Adam, Demakis, Cullen, Dishman, Acacia F., Pillai, Arvind, Idris, Abbas, Juergens, David, Dauparas, Justas, Li, Xinting, Levine, Paul M., Lamb, Mila, Ballard, Ryanne K., Gerben, Stacey R., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Bera, Asim K., Volkman, Brian F., Nivala, Jeff, Stoll, Stefan, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697137/
https://www.ncbi.nlm.nih.gov/pubmed/37590357
http://dx.doi.org/10.1126/science.adg7731

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