Co-factor independent oxidases ncnN and actVA-3 are involved in the dimerization of benzoisochromanequinone antibiotics in naphthocyclinone and actinorhodin biosynthesis

Streptomyces produce complex bioactive secondary metabolites with remarkable chemical diversity. Benzoisochromanequinone polyketides actinorhodin and naphthocyclinone are formed through dimerization of half-molecules via single or double carbon-carbon bonds, respectively. Here we sequenced the genom...

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Detalles Bibliográficos
Autores principales: Baral, Bikash, Matroodi, Soheila, Siitonen, Vilja, Thapa, Keshav, Akhgari, Amir, Yamada, Keith, Nuutila, Aleksi, Metsä-Ketelä, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697411/
https://www.ncbi.nlm.nih.gov/pubmed/37989784
http://dx.doi.org/10.1093/femsle/fnad123

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