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Tissue-resident, extravascular Ly6c(−) monocytes are critical for inflammation in the synovium

Monocytes are abundant immune cells that infiltrate inflamed organs. However, the majority of monocyte studies focus on circulating cells, rather than those in tissue. Here, we identify and characterize an intravascular synovial monocyte population resembling circulating non-classical monocytes and...

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Detalles Bibliográficos
Autores principales: Montgomery, Anna B., Chen, Shang Yang, Wang, Yidan, Gadhvi, Gaurav, Mayr, Maximilian G., Cuda, Carla M., Dominguez, Salina, Makinde, Hadijat-Kubura Moradeke, Gurra, Miranda G., Misharin, Alexander V., Mandelin, Arthur M., Ruderman, Eric M., Thakrar, Anjali, Brar, Simran, Carns, Mary, Aren, Kathleen, Akbarpour, Mahzad, Filer, Andrew, Nayar, Saba, Teososio, Ana, Major, Triin, Bharat, Ankit, Budinger, G.R. Scott, Winter, Deborah R., Perlman, Harris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697497/
https://www.ncbi.nlm.nih.gov/pubmed/37204925
http://dx.doi.org/10.1016/j.celrep.2023.112513