Blockade of EP4 by ASP7657 Modulates Myeloid Cell Differentiation In Vivo and Enhances the Antitumor Effect of Radiotherapy

The tumor microenvironment (TME) is thought to influence the antitumor efficacy of immuno-oncology agents through various products of both tumor and stromal cells. One immune-suppressive factor is prostaglandin E(2) (PGE(2)), a lipid mediator whose biosynthesis is regulated by ubiquitously expressed...

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Detalles Bibliográficos
Autores principales: Nishibata, Toshihide, Amino, Nobuaki, Tanaka-Kado, Ruriko, Tsujimoto, Susumu, Kawashima, Tomoko, Konagai, Satoshi, Suzuki, Tomoyuki, Takeuchi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697779/
http://dx.doi.org/10.1155/2023/7133726

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