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Serum amyloid P component accumulates and persists in neurones following traumatic brain injury

The mechanisms underlying neurodegenerative sequelae of traumatic brain injury (TBI) are poorly understood. The normal plasma protein, serum amyloid P component (SAP), which is normally rigorously excluded from the brain, is directly neurocytotoxic for cerebral neurones and also binds to Aβ amyloid...

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Detalles Bibliográficos
Autores principales: Yip, Ping K., Liu, Zhou-Hao, Hasan, Shumaila, Pepys, Mark B., Uff, Christopher E. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697800/
http://dx.doi.org/10.1098/rsob.230253