A GFP-based reporter system to monitor nonsense-mediated mRNA decay

Aberrant mRNAs whose open reading frame (ORF) is truncated by the presence of a premature translation-termination codon (PTC) are recognized and degraded in eukaryotic cells by a process called nonsense-mediated mRNA decay (NMD). Here, we report the development of a reporter system that allows monit...

Descripción completa

Detalles Bibliográficos
Autores principales: Paillusson, Alexandra, Hirschi, Nadine, Vallan, Claudio, Azzalin, Claus M., Mühlemann, Oliver
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072805/
https://www.ncbi.nlm.nih.gov/pubmed/15800205
http://dx.doi.org/10.1093/nar/gni052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072805/
https://www.ncbi.nlm.nih.gov/pubmed/15800205
http://dx.doi.org/10.1093/nar/gni052

Ejemplares similares