Cargando…

Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages

BACKGROUND: RNA based antiviral approaches against HIV-1 are among the most promising for long-term gene therapy. These include ribozymes, aptamers (decoys), and small interfering RNAs (siRNAs). Lentiviral vectors are ideal for transduction of such inhibitory RNAs into hematopoietic stem cells due t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Banerjea, Akhil, Li, Ming-Jie, Remling, Leila, Rossi, John, Akkina, Ramesh
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074342/ https://www.ncbi.nlm.nih.gov/pubmed/15813986 http://dx.doi.org/10.1186/1742-6405-1-2

Ejemplares similares

HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector
por: Anderson, Joseph, et al.
Publicado: (2005)

Towards a Clinically Relevant Lentiviral Transduction Protocol for Primary Human CD34(+) Hematopoietic Stem/Progenitor Cells
por: Millington, Michelle, et al.
Publicado: (2009)

Lentiviral Transduction of CD34(+) Cells Induces Genome-Wide Epigenetic Modifications
por: Yamagata, Yoshiaki, et al.
Publicado: (2012)

CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection
por: Anderson, Joseph, et al.
Publicado: (2005)

Decitabine Suspends Human CD34(+) Cell Differentiation and Proliferation during Lentiviral Transduction
por: Uchida, Naoya, et al.
Publicado: (2014)

Staurosporine Increases Lentiviral Vector Transduction Efficiency of Human Hematopoietic Stem and Progenitor Cells
por: Lewis, Gretchen, et al.
Publicado: (2018)

Process for an efficient lentiviral cell transduction
por: Pirona, Anna Chiara, et al.
Publicado: (2020)

Zika virus induced microcephaly and aberrant hematopoietic cell differentiation modeled in novel neonatal humanized mice
por: Schmitt, Kimberly, et al.
Publicado: (2023)

Cyclosporine H Improves the Multi-Vector Lentiviral Transduction of Murine Haematopoietic Progenitors and Stem Cells
por: Olender, Leonid, et al.
Publicado: (2020)

Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice
por: Schmitt, Kimberly, et al.
Publicado: (2020)

A dual function TAR Decoy serves as an anti-HIV siRNA delivery vehicle
por: Unwalla, Hoshang J, et al.
Publicado: (2010)

Optimized protocols for γδ T cell expansion and lentiviral transduction
por: Wang, Rui-Ning, et al.
Publicado: (2019)

Functional characterization of HIV-1 Tat exon-1 variants from North India and their implications on HIV-1 transactivation and TAR interaction
por: Ronsard, Larance, et al.
Publicado: (2014)

Prostaglandin E(2) Increases Lentiviral Vector Transduction Efficiency of Adult Human Hematopoietic Stem and Progenitor Cells
por: Heffner, Garrett C., et al.
Publicado: (2018)

High-Efficiency Lentiviral Transduction of Human CD34(+) Cells in High-Density Culture with Poloxamer and Prostaglandin E2
por: Uchida, Naoya, et al.
Publicado: (2019)

Identification of a small molecule for enhancing lentiviral transduction of T cells
por: Malach, Paulina, et al.
Publicado: (2023)

Lentiviral vector-mediated transduction of adult neural stem/progenitor cells isolated from the temporal tissues of epileptic patients
por: Abdolahi, Sara, et al.
Publicado: (2020)

Purification of Human CD34(+)CD90(+) HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy
por: Radtke, Stefan, et al.
Publicado: (2020)

In silico Analyses of Subtype Specific HIV-1 Tat-TAR RNA Interaction Reveals the Structural Determinants for Viral Activity
por: Ronsard, Larance, et al.
Publicado: (2017)

Driving DNA transposition by lentiviral protein transduction
por: Cai, Yujia, et al.
Publicado: (2014)

Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells
por: Chen, Xiaochuan, et al.
Publicado: (2004)

A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells
por: Delville, Marianne, et al.
Publicado: (2018)

Inhibition of HIV derived lentiviral production by TAR RNA binding domain of TAT protein
por: Mi, Michael Y, et al.
Publicado: (2005)

Lentiviral vector induces high-quality memory T cells via dendritic cells transduction
por: Ku, Min Wen, et al.
Publicado: (2021)

Avoiding lentiviral transduction culture induced MSC senescence
por: Pan, Yung-Wei, et al.
Publicado: (2009)

In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
por: Marodon, Gilles, et al.
Publicado: (2004)

Polybrene Inhibits Human Mesenchymal Stem Cell Proliferation during Lentiviral Transduction
por: Lin, Paul, et al.
Publicado: (2011)

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression
por: Nicholls, Peter K., et al.
Publicado: (2012)

Improving the Transduction of Bone Marrow–Derived Cells with an Integrase-Defective Lentiviral Vector
por: Pay, S. Louise, et al.
Publicado: (2018)

Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application
por: Schott, Juliane W., et al.
Publicado: (2019)

Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment
por: Schimmer, Aaron D., et al.
Publicado: (2020)

Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance
por: Tamhane, Mayur, et al.
Publicado: (2008)

Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors
por: Salomonsson, Maya, et al.
Publicado: (2020)

Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs via a Chemically Synthesized Aptamer With a Sticky Bridge
por: Zhou, Jiehua, et al.
Publicado: (2013)

Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles
por: Link, Nils, et al.
Publicado: (2006)

Simplified production and concentration of lentiviral vectors to achieve high transduction in primary human T cells
por: Cribbs, Adam P, et al.
Publicado: (2013)

A first experience of transduction for differentiated HepaRG cells using lentiviral technology
por: Pivert, Adeline, et al.
Publicado: (2019)

Highly efficient ex vivo lentiviral transduction of primary human pancreatic exocrine cells
por: Balak, Jeetindra R. A., et al.
Publicado: (2019)

Minimal impact of ZAP on lentiviral vector production and transduction efficiency
por: Sertkaya, Helin, et al.
Publicado: (2021)

Efficient Transduction of Feline Neural Progenitor Cells for Delivery of Glial Cell Line-Derived Neurotrophic Factor Using a Feline Immunodeficiency Virus-Based Lentiviral Construct
por: You, X. Joann, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_78p8g66v2mk5v2i91tr5visc35